The purpose of this project is to prepare skin tissue engineering scaffolds with good biological and mechanical properties by utilizing the high biocompatibility, antibacterial properties and the ability to promote cell proliferation and differentiation, and to repair and regenerate skin defects by modifying growth factors and stem cells.

This project aims to realize sensitive detection of tumor-related biomarkers (such as miRNA, circulating tumor cells, etc.) by utilizing the high fluorescence, low toxicity, and functionability of nanocarbon dots, and improve the accuracy and sensitivity of detection by designing signal amplification strategies (such as DNase, nucleic acid probes, etc.).

This project aims to use single-cell metabolomics technology to detect and quantify metabolites in tumor cells at the single-cell level, reveal the metabolic heterogeneity and plasticity of tumor cells under internal and external environment, analyze the correlation between tumor cell metabolites and gene expression, signaling pathway, epigenetics and other levels of information, and explore the metabolic regulatory mechanisms and metabolic targets of tumor cells. To provide a new strategy and means for tumor diagnosis and treatment.

The purpose of this project is to use the self-healing ability and flexibility of self-healing polymer materials to develop flexible wearable sensors with high sensitivity, high stability and high reliability, which can be applied to the monitoring and intelligent interaction of human physiological signals, and to study its sensing mechanism and function optimization strategy.