Life Sciences - Micro-nanorobots based on multi-field response hydrogels
Background: Hydrogel is a kind of three-dimensional cross-linked polymer network containing a lot of water, which has the characteristics of softness, elasticity and biocompatibility, and is suitable for making micro-nano robots. Micro-nanorobots are tiny devices capable of performing specific tasks at the micro or nano scale, which can be applied in biomedicine, environmental monitoring, material synthesis and other fields. Multi-field response hydrogel is a kind of hydrogel that can respond to multiple external stimuli (such as temperature, light, electricity, magnetism, etc.) simultaneously or sequentially, and can achieve complex deformation and function.
Project information: This project aims to use multi-field response hydrogels to prepare micro-nanorobots, and explore their movement and interaction behavior under different stimulus conditions, as well as their application prospects in the simulated biological environment in vivo.
Project content:
Multi-field response hydrogels (such as polyvinylpyrrolidone/polyethylene glycol/ferrite composite hydrogels) and other functional materials (such as metal nanoparticles, fluorescent dyes, etc.) are assembled into micro-nanorobots by self-assembly method.
The deformation and motion characteristics of micro-nano robots under different stimuli (such as temperature change, illumination, alternating magnetic field, etc.) were observed and recorded by optical microscope and high-speed camera, and the mechanical mechanism and dynamic model were analyzed.
The interaction between micro and nano robots and the surrounding media is studied by experiments and simulation methods, and the group behavior and synergistic effect are discussed.
By building an experimental platform that simulates the biological environment in vivo (such as blood vessels, cell culture, etc.), the biocompatibility and safety of micro-nanorobots are evaluated, and their functions and effects in drug delivery, imaging diagnosis, and wound repair are tested.
Topic innovation:
The multi-field response hydrogel is used as the main material of micro-nano robot, which improves its adaptability and intelligence to complex environment, and realizes the integration of various deformation and functions.
Micro-nano robots with different morphologies and structures were prepared by self-assembly method, which simplified the preparation process, reduced the cost and increased the controllability.
The motion and interaction behavior of micro-nano robots under different stimulation conditions are systematically studied, and the force mechanism and dynamics rules are revealed, which provides a theoretical basis for optimal design and control.
The application prospect of micro - and nanorobots in simulating the environment in vivo is explored, which provides a new idea for developing new life science instruments and methods.
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